{"id":3280,"date":"2021-11-18T12:49:20","date_gmt":"2021-11-18T11:49:20","guid":{"rendered":"https:\/\/www.curavac.com\/maladies-auto-immunes"},"modified":"2025-04-11T15:58:24","modified_gmt":"2025-04-11T13:58:24","slug":"maladies-auto-immunes","status":"publish","type":"page","link":"https:\/\/www.curavac.com\/fr\/maladies-auto-immunes","title":{"rendered":"Maladies auto-immunes"},"content":{"rendered":"

Maladies auto-immunes<\/h2>\n

Les maladies auto-immunes<\/strong> sont des affections dans lesquelles le syst\u00e8me immunitaire se retourne par erreur contre certaines parties de l’organisme comme s’il s’agissait de cellules \u00e9trang\u00e8res nuisibles. En r\u00e9ponse \u00e0 un d\u00e9clencheur inconnu, qui peut \u00eatre de nature environnementale ou g\u00e9n\u00e9tique, le syst\u00e8me immunitaire commence \u00e0 produire des anticorps qui, au lieu de combattre les infections, attaquent les propres tissus de l’organisme.<\/p>\n

Il existe de nombreuses maladies auto-immunes, environ 80, dont les sympt\u00f4mes vont de l\u00e9gers \u00e0 invalidants, selon la partie du corps touch\u00e9e et le degr\u00e9 d’atteinte. On estime que 5 \u00e0 8 % de la population mondiale souffre actuellement d’une maladie auto-immune. Parmi les plus r\u00e9pandues, on trouve la maladie de Graves<\/strong>, la maladie de Hashimoto<\/strong>, le diab\u00e8te de type 1<\/strong>, la scl\u00e9rose en plaques<\/strong> (SEP), le lupus \u00e9ryth\u00e9mateux diss\u00e9min\u00e9<\/strong> (LED) et la myasth\u00e9nie grave<\/strong> (MG).<\/p>\n

Maladies auto-immunes – Nombre de cas aux \u00c9tats-Unis<\/h2>\n

Maladie de Grave
\n2,064,600
\nMaladie de Hashimoto
\n1,731,600
\nDiab\u00e8te de type 1
\n865,800
\nScl\u00e9rose en plaques
\n799,200
\nLupus syst\u00e9mique
\n233,100
\nMyasth\u00e9nie Grave
\n66,600<\/p>\n

CuraVac<\/strong> concentre initialement ses recherches sur une th\u00e9rapie active cibl\u00e9e pour<\/strong> la myasth\u00e9ni<\/strong>e<\/strong>, une maladie auto-immune rare mais pas exceptionnelle qui touche environ une personne sur cinq \u00e0 cinq mille dans le monde. Bien qu’elle ne soit pas tr\u00e8s r\u00e9pandue, la pathologie de la MG est tr\u00e8s bien comprise et constitue un excellent mod\u00e8le de d\u00e9veloppement pour d’autres th\u00e9rapies actives cibl\u00e9es contre les maladies auto-immunes.<\/p>\n

Actuellement, les traitements des maladies auto-immunes n\u00e9cessitent souvent des m\u00e9dicaments lourds ou des proc\u00e9dures chirurgicales invasives, souvent accompagn\u00e9s de nombreux effets secondaires. La plupart du temps, ces traitements ne peuvent que r\u00e9duire certains sympt\u00f4mes ou ralentir la progression de la maladie.<\/p>\n

Le succ\u00e8s de la premi\u00e8re th\u00e9rapie active cibl\u00e9e de CuraVac repr\u00e9sente une avanc\u00e9e potentielle<\/strong> dans le domaine des maladies auto-immunes et pourrait ouvrir la voie \u00e0 un nouveau type de traitement, susceptible d’offrir une am\u00e9lioration durable et d’apporter un rem\u00e8de potentiel aux patients.<\/p>\n

Les r\u00e9sultats finaux de notre essai clinique de phase 1B <\/a>ont d\u00e9montr\u00e9 un excellent profil de s\u00e9curit\u00e9 et ont appel\u00e9 \u00e0 un essai clinique d’efficacit\u00e9 de phase 2 que nous pr\u00e9parons actuellement avec une formulation plus puissante de la Th\u00e9rapie Active Cibl\u00e9e contre la MG : CV-MG02.<\/p>\n","protected":false},"excerpt":{"rendered":"

Maladies auto-immunes Les maladies auto-immunes sont des affections dans lesquelles le syst\u00e8me immunitaire se retourne par erreur contre certaines parties de l’organisme comme s’il s’agissait de cellules \u00e9trang\u00e8res nuisibles. En r\u00e9ponse \u00e0 un d\u00e9clencheur inconnu, qui peut \u00eatre de nature environnementale ou g\u00e9n\u00e9tique, le syst\u00e8me immunitaire commence \u00e0 produire des anticorps qui, au lieu de …<\/p>\n

Maladies auto-immunes<\/span> Lire la suite\u00a0\u00bb<\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"site-sidebar-layout":"no-sidebar","site-content-layout":"page-builder","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"disabled","ast-breadcrumbs-content":"","ast-featured-img":"disabled","footer-sml-layout":"","theme-transparent-header-meta":"","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","footnotes":""},"class_list":["post-3280","page","type-page","status-publish","hentry"],"yoast_head":"\nMaladies auto-immunes - CuraVac<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.curavac.com\/autoimmune-diseases\" \/>\n<meta property=\"og:locale\" content=\"fr_FR\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Maladies auto-immunes - CuraVac\" \/>\n<meta property=\"og:description\" content=\"Maladies auto-immunes Les maladies auto-immunes sont des affections dans lesquelles le syst\u00e8me immunitaire se retourne par erreur contre certaines parties de l’organisme comme s’il s’agissait de cellules \u00e9trang\u00e8res nuisibles. 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